Molecule card · MolClass #92419

AZM418

AZM418: molecular structure, identifiers, source datasets and 0 saved model results in MolClass.

1 source records · 0 model builds with saved results

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Structure and identifiers

MolClass ID: 92419
InChIKey: PREVLKLSVWYCAY-QGZVFWFLSA-N
Canonical SMILES: [H]C(O)(CNC(=O)C2=CNC(=O)c1ccccc12)CN3CCC(CC3)Oc4ccc(C#N)c(c4)Cl
Standard InChI: InChI=1S/C25H25ClN4O4/c26-23-11-19(6-5-16(23)12-27)34-18-7-9-30(10-8-18)15-17(31)13-28-25(33)22-14-29-24(32)21-4-2-1-3-20(21)22/h1-6,11,14,17-18,31H,7-10,13,15H2,(H,28,33)(H,29,32)/t17-/m1/s1
Stored Murcko scaffold: O(c1ccccc1)C2CCN(CCCN[CH]C3=CN[CH]c4ccccc43)CC2

Registry normalization: MIGRATED_RAW. A registry entry does not establish drug approval or clinical use.

Molecules with the same Murcko scaffold

Exact matches to the stored ring-and-linker framework. Sharing a scaffold does not by itself establish activity or applicability to a model.

AZM305#92308
AZM426#92426
AZM427#92427
AZM428#92428
AZM430#92430
AZM431#92431
AZM432#92432
AZM438#92438
AZM440#92440
AZM467#92466
AZM468#92467
AZM469#92468
AZM481#92479
AZM485#92483

Calculated molecular properties

Stored descriptor calculations, not measured experimental values.

Hydrogen bond acceptors: 7; CDK 2.12 · 2026-08-19
Hydrogen bond donors: 3; CDK 2.12 · 2026-08-19
Rotatable bonds: 8; CDK 2.12 · 2026-08-19
Topological polar surface area: 114.69 Å²; CDK 2.12 · 2026-08-19
Molecular weight: 480.944 g/mol; CDK 2.12 · 2026-08-19
XLogP: 3.103; CDK 2.12 · 2026-08-19

Saved model predictions

Computational predictions, not experimental measurements or clinical guidance. Results depend on the model build; applicability indicates similarity to its training chemistry.

No saved predictions yet. Explore classification models to choose a prediction.

Source datasets

Dataset registrations and identifiers stored in MolClass.

Microsome Clearance (AZ Hackathon)
Dataset #31 · AZM418